University of Oxford

The University of Oxford (formally The Chancellor, Masters and Scholars of the University of Oxford) is a collegiate research university located in Oxford, England. The University is made up of a variety of institutions, including 38 constituent colleges and a full range of academic departments which are organised into four divisions. Being a city university, it does not have a main campus and instead its buildings and facilities are scattered throughout the city centre. Most undergraduate teaching at Oxford is organised around weekly tutorials at the colleges and halls, supported by classes, lectures and laboratory work provided by university faculties and departments. The University operates the world’s oldest university museum, as well as the largest university press in the world and the largest academic library system in Britain. Oxford has educated many notable alumni, including 29 Nobel laureates, 27 Prime Ministers of the United Kingdom and many heads of state and government around the world. 69 Nobel Prize winners have studied, worked, or held visiting fellowships at the University of Oxford. UOXF has comprehensive expertise in the development and application of hyperpolarised magnetic resonance imaging and spectroscopy with a particular focus on cardiovascular applications

Role in project

UOXF will be involved in the testing of novel hyperpolarised compounds, the development of novel pulse sequences and the validation of the developed approaches in pre-clinical models of cardiovascular disease.

University of Cambridge

The University of Cambridge is one of the world’s oldest universities and leading academic centres, and a self-governed community of scholars. Its reputation for outstanding academic achievement is known world-wide and reflects the intellectual achievement of its students, as well as the world-class research carried out by the staff.

The Cancer Research UK Cambridge Institute (CRUK CI) focuses on tackling questions relating to cancer diagnosis, treatment and prevention, supported by world-class scientific facilities. Our aim is to be a focus for the practical application of high-quality research, forming a bridge between the University of Cambridge and Addenbrooke’s Hospital. The Institute’s location on the Cambridge Biomedical Campus and its membership of many collaborative initiatives are vital in helping us to achieve our goals.

The Cambridge Biomedical Campus is home to Addenbrooke’s Hospital, the University of Cambridge teaching hospital, and many of our collaborating institutes, including the MRC Laboratory for Molecular Biology, the Hutchison/MRC Research Centre, the Strangeways Research Laboratories for Genetic Epidemiology and the Cambridge Institute for Medical Research. In the wider Cambridge area we also have extensive links with the Wellcome Trust Sanger Institute, and the European Bioinformatics Institute.

CRUK CI is a key member of the Cambridge Cancer Centre: a partnership between the University of Cambridge, Cancer Research UK, Cambridge University Hospitals NHS Foundation Trust and Cambridge University Health Partners. The aim of the centre is to bring together researchers in biology, medicine, maths, physics, chemistry and biology, as well as clinicians and pharmaceutical companies from across the Cambridge region, whose research has implications for the prevention, detection or treatment of cancer. A key focus of the centre is translating the work done in Cambridge laboratories into benefits for patients in the clinic. The Cambridge Cancer Centre is also a member of the Organisation of European Cancer Institutes (OECI).  UCAM has 40 years of experience in the application of magnetic resonance techniques to biological systems

Role in project

UCAM will conduct studies with hyperpolarised 13C-labelled cell substrates in animal models of disease and in cancer patients.