Alternatives to GD
The AlternativesToGd project is developing a new type of contrast agent for medical imaging which is safe and completely cleared from the body.
Current generation contrast agents rely on Gadolinium, which has raised major health concerns resulting from long-term accumulation in patients’ bodies.
About the Project
AlternativesToGd is a three-year collaborative research project. It brings together highly experienced engineers, physicists, chemists and radiologists to develop a radically new and innovative contrast agent for magnetic resonance imaging.
These contrast agents that will be metal-free, small endogenous molecules, which are hyperpolarised to ensure high sensitivities even at very low doses.
Our multidisciplinary consortium combines the expertise of ten partners from six countries. It includes major universities, research institutes and industry partners.
To find out more about our consortium and its researchers, click on the country on the map below to see the individual partners. On each country’s page you can read more details about the consortium’s members.
Find all our research results, public data, press publications and media here.
View our Research Results
Our scientific publications, and datasets used for those publications, are published free of any restrictions on access.
Press and Media
Download all our promotional materials, such as flyers and folders, and read our press releases.
Stay up to date on the AlternativesToGd project.
We will periodically share news on research developments, publications, presentations and more. For more updates, be sure to follow the project on social media as well using the #AlternativesToGd.
Publication news: September 2020
On September 3, 2020, an author’s manuscript with results on the hyperpolarization of fumarate was published to a pre-print server, pending peer review.
Project receives extension
On September 3, 2020, the AlternativesToGd project received a cost-neutral, 12-month extension from the European Commission due to delays caused by the COVID-19 pandemic.
Publication news: July 2020
Three new papers with project results have been published: one on hyperpolarized water through dDNP with UV-generated radicals, one on laser-synthesis of NV-centers-enriched nanodiamonds, and one on synthesis of nanodiamonds from adamantane “seeds”.
First project publication
The first paper with AlternativesToGd results has been published on March 10, 2020! This reports results on hyperpolarized 15-N2-urea detection.
If you have any additional questions, or would like to receive more in-depth information on AlternativesToGd, don’t hesitate to get in touch with us!
Rachel Katz-Brull is an Associate Professor of Imaging at the Hebrew University Faculty of Medicine and the Director of the Centre for Hyperpolarised MRI Molecular Imaging at Hadassah’s Ein-Kerem campus in Jerusalem, Israel, and the project coordinator of AlternativesToGd. She has 25 years of experience in the field of biomedical nuclear magnetic resonance imaging and spectroscopy and has been focusing on hyperpolarised MRI in the last 10 years.
Peter Gordebeke is a project manager at the European Institute for Biomedical Imaging Research, and leads the communication and dissemination activities of AlternativesToGd. He has done research in RNA biology in both academic and industry settings, and has past experience in project management of clinical studies, and EU-funded research.